Dr. Isaac George, MD joined NewYork Presbyterian/Columbia University Medical Center in the Department of Surgery in July of 2001 as a resident in general surgery following his graduation from Duke University School of Medicine. Prior to receiving his MD, Dr. George completed a B.S. in Mechanical Engineering at Massachusetts Institute of Technology in 1997. Dr. George also completed a fellowship program in cardiothoracic surgery in 2011 as well as a fellowship program in interventional cardiology in 2012. In July, 2012 Dr. George became an Assistant Professor of Surgery and later an Assistant Professor of Medicine.

Dr. George is board certified in thoracic (cardiac) surgery and general surgery. He performs all types of open and reoperative adult cardiac surgery (aortic, mitral and tricuspid valve surgery, aortic aneurysm surgery, coronary bypass grafting, robotic surgery) with a particular interest in complex valvular and aortic disease.  He specializes in minimally invasive mitral valve surgery with small incisions and repair of the mitral valve.  He annually performs 150-200+ open heart surgeries a year and is one of the few physicians in the world trained in both cardiac surgery and interventional cardiology.  Dr. George is currently the Surgical Director of the Structural Heart and Valve Center at Columbia University Irving Medical Center. His surgical outcomes remain some of the best in the state despite taking on the highest risk cases (surgical mortality rate per year 1.5-2%). 

Dr. George is focused on integrating new technology and innovation into his clinical practice. He is trained in the most current and cutting-edge procedures including Transcatheter Valve Replacement (TAVR, TMVR), transcatheter valvular repair (Mitraclip), percutaneous coronary stenting, and aortic stent grafting. He performs almost 800 transcatheter valve procedures a year, in addition to his busy open surgical practice and has personally done almost 6000 TAVR procedures. Because he is trained in multiple disciplines, he is able to combine strategies to create a treatment plan for each individual patient that is both unbiased and personalized. As Primary Investigator of a national TAVR trial and with involvement in numerous other clinical trials, he has extensive clinical research trial experience.